zamushwani

Analyze Degs — Development skill for Claude Code

Development community

Differential expression from a count matrix with DESeq2. Use when the user has bulk RNA-seq counts and wants DEGs, a volcano plot, or asks which genes differ between conditions.

How to install Analyze Degs

Installs to ~/.claude/commands/zamushwani-biomedical-ai-skills-analyze-degs.md

Terminal

mkdir -p ~/.claude/commands && curl -fsSL https://raw.githubusercontent.com/zamushwani/biomedical-ai-skills/HEAD/.claude/commands/analyze-degs.md -o ~/.claude/commands/zamushwani-biomedical-ai-skills-analyze-degs.md

Restart Claude Code, or start a new session, for it to be picked up.

What Analyze Degs does

description: Differential expression from a count matrix with DESeq2. Use when the user has bulk RNA-seq counts and wants DEGs, a volcano plot, or asks which genes differ between conditions. argument-hint: [counts-file] [condition-column] allowed-tools: Read Grep Glob Bash(Rscript *)

Run a differential expression analysis on `$0` using the condition column `$1`.

Follow the `cancer-multiomics` skill. The parts that are usually got wrong:

Feed DESeq2 raw integer counts. Not TPM,

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