tomtommyyuan

Spmind — AI skill for Claude Code

AI community

[ICML 2026] Autonomous AI agent for end-to-end spatial proteomics analysis, with SP-Bench for agentic multiplexed-imaging workflows.

How to install Spmind

This entry records only its repository, not the path inside it, so there is no exact command to give. Open tomtommyyuan/spmind and copy the folder into ~/.claude/skills/, or the file into ~/.claude/agents/.

What Spmind does

[ICML 2026] Autonomous AI agent for end-to-end spatial proteomics analysis, with SP-Bench for agentic multiplexed-imaging workflows.

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README

🧬 SP-Mind: An Autonomous Reasoning Agent for Spatial Proteomics (ICML 2026)

▶ 55-second overview — if the player doesn't load, watch the demo video.

SP-Mind overview: from raw multiplexed imaging through the agent's skill-guided pipeline to downstream phenotype discovery and benchmark results

Abstract

Spatial proteomics enables single-cell-resolution characterization of protein expression within tissue architecture, playing a critical role in understanding tumor microenvironments and guiding precision medicine. However, current analysis workflows remain fragmented, requiring expert manual orchestration of heterogeneous tools and limiting research scalability and reproducibility. We present SP-Mind, the first autonomous AI agent designed to unify the spatial proteomics analysis pipeline, from raw multiplexed tissue imaging to downstream phenotype discovery. Equipped with expert-curated biological analysis skills and specialized computational tools, SP-Mind converts natural-language q