htlin222

Drug Drug Skill — Development skill for Claude Code

Development community

Evidence-based Drug-Drug Interaction (DDI) assessment skill modeled after Micromedex Drug-Reax.

How to install Drug Drug Skill

This entry records only its repository, not the path inside it, so there is no exact command to give. Open htlin222/drug-drug-skill and copy the folder into ~/.claude/skills/, or the file into ~/.claude/agents/.

What Drug Drug Skill does

Evidence-based Drug-Drug Interaction (DDI) assessment skill modeled after Micromedex Drug-Reax. Install: npx skills add htlin222/drug-drug-skill

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README

drug-drug

[![Build & Release Skill](https://github.com/htlin222/drug-drug-skill/actions/workflows/release.yml/badge.svg)](https://github.com/htlin222/drug-drug-skill/actions/workflows/release.yml) [![GitHub Release](https://img.shields.io/github/v/release/htlin222/drug-drug-skill?include_prereleases&label=skill%20version)](https://github.com/htlin222/drug-drug-skill/releases/latest) [![License: CC BY 4.0](https://img.shields.io/badge/License-CC%20BY%204.0-lightgrey.svg)](https://creativecommons.org/licenses/by/4.0/) [![Skills Protocol](https://img.shields.io/badge/protocol-vercel--labs%2Fskills-blue)](https://github.com/vercel-labs/skills) [![Compatible Agents](https://img.shields.io/badge/agents-40%2B-green)](https://github.com/vercel-labs/skills#supported-agents)

Evidence-based Drug-Drug Interaction (DDI) assessment skill modeled after the Micromedex Drug-Reax methodology.

Install

npx skills add htlin222/drug-drug-skill
npx skills add -g htlin222/drug-drug-skill        # global
npx skills add htlin222/drug-drug-skill --agent claude-code  # specific agent

What it does

This skill performs systematic Drug-Drug Interaction assessments using real-time literature retrieval from PubMed, CrossRef, and web sources. It produces structured reports following the Micromedex Drug-Reax classification framework, including:

Severity grading: Contraindicated / Major / Moderate / Minor
Documentation grading: Excellent / Good / Fair / Poor / Unlikely
Onset classification: Rapid / Delayed / Not specified
Mechanism analysis: Pharmacokinetic (CYP450, P-gp, renal) and Pharmacodynamic (additive, synergistic, antagonistic)
Clinical management recommendations with monitoring parameters and alternatives

Triggered by `/drug-drug DrugA DrugB` or natural language queries about drug interactions.