Brenner Bot

Brenner Bot

**🌐 Live at [brennerbot.org](https://brennerbot.org)**

[](https://codecov.io/gh/Dicklesworthstone/brenner_bot)

Harness the scientific methods of Sydney Brenner using AI Agents

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**Brenner Bot is a research "seed crystal"**: a curated primary-source corpus (Sydney Brenner transcripts) plus multi-model syntheses, powering **collaborative scientific research conversations** that follow the "Brenner approach."

📊 **[End-to-End Test Report: Bio-Inspired Nanochat Session](./ANALYSIS_OF_USING_BRENNERBOT_FOR_BIO_INSPIRED_NANOCHAT.md)** — A complete walkthrough demonstrating the Brenner method in action on a real research question about biological vs. synthetic nanoparticle communication.

The north star

This repository integrates with **Agent Mail** (coordination + memory + workflow glue) so multiple coding agents can collaborate as a *research group*:

• Claude Code running Opus 4.5
• Codex CLI running GPT‑5.2 (extra-high reasoning)
• Gemini CLI running Gemini 3

**Critical constraint (non-negotiable):** We do **not** call vendor AI APIs from code. Instead, we coordinate CLI tools via their **subscription tiers** (Claude Max / GPT Pro / Gemini Ultra) running in terminal sessions. Orchestration is *message passing + compilation*, not remote inference.

The agents run in parallel via **ntm** (Named Tmux Manager), coordinating through **Agent Mail** threads, producing structured deltas that get compiled into durable artifacts.

The system includes:

• A Next.js web app at brennerbot.org — human interface for corpus browsing + session viewing (not agent execution)
• A Bun CLI (brenner) — terminal-first workflows for power users
• A cockpit runtime — ntm-based multi-agent