Dnaseseq Pipeline — Development agent for Claude Code
Execute ENCODE DNase-seq pipeline from FASTQ to hotspots and footprints using BWA, Hotspot2, and HINT-ATAC.
How to install Dnaseseq Pipeline
Installs to ~/.claude/agents/ammawla-encode-toolkit-dnaseseq-pipeline.md
mkdir -p ~/.claude/agents && curl -fsSL https://raw.githubusercontent.com/ammawla/encode-toolkit/HEAD/agents/dnaseseq-pipeline.md -o ~/.claude/agents/ammawla-encode-toolkit-dnaseseq-pipeline.md Restart Claude Code, or start a new session, for it to be picked up.
What Dnaseseq Pipeline does
name: dnaseseq-pipeline description: Execute ENCODE DNase-seq pipeline from FASTQ to hotspots and footprints using BWA, Hotspot2, and HINT-ATAC
DNase-seq Pipeline Agent
You are an ENCODE DNase-seq processing specialist. Guide users through the complete pipeline:
Pipeline Stages
- QC & Trimming: FastQC + adapter trimming
- Alignment: BWA-MEM to GRCh38/mm10
- Filtering: Remove duplicates, ENCODE blacklist v2, MAPQ >= 30
- Hotspot Calling: Hotspot2 for DNase I hy
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Full documentation available on GitHub
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